{"id":5909,"date":"2017-08-01T18:12:29","date_gmt":"2017-08-01T22:12:29","guid":{"rendered":"http:\/\/localhost:10028\/practiceareas\/diethylstilbestrol-des\/"},"modified":"2022-06-21T16:54:49","modified_gmt":"2022-06-21T20:54:49","slug":"dietylostilbestrol-des","status":"publish","type":"practiceareas","link":"https:\/\/napolilaw.lemonadestand.org\/pl\/teren-do-cwiczen-2\/dietylostilbestrol-des\/","title":{"rendered":"DES Daughters"},"content":{"rendered":"<h2>C\u00f3rki DES i powa\u017cne obra\u017cenia<\/h2>\n<p>Doctors once considered Diethylstilbestrol to be something of a miracle drug which could all but end most pregnancy complications, but instead of a panacea, the drug created an entire generation of victims.<\/p>\n<p>The synthetic estrogen was created in 1938, and after a brief series of clinical trials, the Food and Drug Administration allowed doctors to prescribe it to pregnant women in 1947. At the time, many doctors believed that low estrogen levels caused most pregnancy complications, and even though that idea was somewhat debunked by the 1950s (and is entirely debunked today), doctors kept administering it in large quantities.<\/p>\n<p>About that same time, researchers began to question DES\u2019 safety, leading to a 1971 FDA declaration that the drug was <a href=\"https:\/\/www.cdc.gov\/des\/consumers\/about\/history.html\" target=\"_blank\" rel=\"noopener noreferrer\">nieodpowiednie dla kobiet w ci\u0105\u017cy<\/a>. Ale recepty trwa\u0142y jeszcze przez kilka lat, poniewa\u017c agencja nie wycofa\u0142a leku.<\/p>\n<p>&nbsp;<\/p>\n<h3>C\u00f3rki DES (i Synowie DES)<\/h3>\n<p>In the 1940s and 1950s, many pregnant women went to general practitioners. These doctors probably had no idea that they were prescribing a powerful drug which was, at best, only marginally effective.<\/p>\n<p>The FDA took adverse action against DES based on a 1971 study which linked Diethylstilbestrol with vaginal clear cell adenocarcinoma, an unusual and aggressive form of <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJM197104222841604\" target=\"_blank\" rel=\"noopener noreferrer\">rak szyjki macicy<\/a> jest trudny do leczenia i charakteryzuje si\u0119 wysok\u0105 \u015bmiertelno\u015bci\u0105. C\u00f3rki DES lub kobiety, kt\u00f3re by\u0142y nara\u017cone na dzia\u0142anie leku w macicy, rozwija\u0142y t\u0119 chorob\u0119 w niepokoj\u0105co wysokim tempie. Przez lata dietylostilbestrol by\u0142 r\u00f3wnie\u017c powi\u0105zany z innymi powa\u017cnymi problemami zdrowotnymi, w tym:<\/p>\n<ul>\n<li><strong>Niep\u0142odno\u015b\u0107 i zdrowie reprodukcyjne<\/strong>: Naukowcy sklasyfikowali DES jako teratogen, grup\u0119 substancji, kt\u00f3re zasadniczo zatruwaj\u0105 macic\u0119. W p\u00f3\u017aniejszym okresie \u017cycia kobiety, kt\u00f3re by\u0142y nara\u017cone na dzia\u0142anie leku w okresie p\u0142odowym, cz\u0119sto borykaj\u0105 si\u0119 z r\u00f3\u017cnymi problemami zwi\u0105zanymi z reprodukcj\u0105, w tym ci\u0105\u017c\u0105 pozamaciczn\u0105, porodem przedwczesnym i spontaniczn\u0105 aborcj\u0105.<\/li>\n<li><strong>Rak piersi<\/strong>: ekspozycja na DES zwi\u0119ksza ryzyko raka piersi, chocia\u017c nie w stopniu gruczolakoraka jasnokom\u00f3rkowego pochwy.<\/li>\n<li><strong>Oty\u0142o\u015b\u0107<\/strong>: DES jest r\u00f3wnie\u017c znanym czynnikiem powoduj\u0105cym oty\u0142o\u015b\u0107, wi\u0119c ofiary cz\u0119sto rozwijaj\u0105 niewyja\u015bnion\u0105 oty\u0142o\u015b\u0107 w wieku doros\u0142ym.<\/li>\n<\/ul>\n<p>Synowie DES maj\u0105 podobne problemy, poniewa\u017c cz\u0119\u015bciej zapadaj\u0105 na raka j\u0105der, niep\u0142odno\u015b\u0107 i niski poziom testosteronu.<\/p>\n<p>&nbsp;<\/p>\n<h3>DES Wnuczki<\/h3>\n<p>Researchers now know that DES is an epigenetic drug that actually has the power to alter a person\u2019s genetic code. As a result, the physical abnormalities that affect DES daughters and sons may affect their children as well. Many researchers fear that these effects may continue indefinitely as they are passed down from parents to children.<\/p>\n<p>The good news is that the side effects seem to have diminished somewhat, as DES granddaughters and grandsons are likely to have fertility issues but, so far, are not more prone to reproductive cancer. The bad news is that the psychological effects of DES exposure, such as <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20332145\" target=\"_blank\" rel=\"noopener noreferrer\">ci\u0119\u017cka depresja<\/a>, mo\u017ce by\u0107 jeszcze gorzej.<\/p>\n<p>&nbsp;<\/p>\n<h3>Roszczenia o odszkodowanie<\/h3>\n<p>Because the DES exposure occurred so many years ago, one would think that these cases would be difficult to prove. But two plaintiff-friendly legal rules make the process much easier.<\/p>\n<p>One is the <a href=\"http:\/\/scholarship.law.missouri.edu\/cgi\/viewcontent.cgi?article=1187&amp;context=facpubs\" target=\"_blank\" rel=\"noopener noreferrer\">odpowiedzialno\u015b\u0107 za udzia\u0142 w rynku<\/a> doctrine. This rule is now widely used in products liability cases but was actually conceived in a DES daughters case. In most of these cases, the victim\/plaintiff names several potential defendants but, through no fault of his or her own, the victim\/plaintiff cannot identify the actual tortfeasor (company which sold DES to the victim\/plaintiff\u2019s mother). If a substantial share of the possibly responsible companies are named in the lawsuit and the jury awards damages, each defendant is responsible for a share of damages based on its market share at the time the drug was sold.<\/p>\n<p>Another key doctrine is the <a href=\"http:\/\/digitalcommons.law.scu.edu\/cgi\/viewcontent.cgi?article=1930&amp;context=lawreview\" target=\"_blank\" rel=\"noopener noreferrer\">regu\u0142a odkrywania<\/a>. This principle states that the three-year statute of limitations is tolled (suspended) until the victim knows about the injury and has a plausible reason to connect that injury with someone else\u2019s negligence.<\/p>\n<p>Successful plaintiffs are normally entitled to compensatory damages for medical bills, lost wages, emotional distress, loss of enjoyment in life, and other consequential damages, as well as significant punitive damages which punish the tortfeasor\u2019s wrongful conduct and help deter others from doing the same thing.<\/p>\n<p>DES daughters must often deal with lifelong and\/or serious injuries. For a free consultation with a <a href=\"\/pl\/spory-farmaceutyczne\/\">adwokat w sprawach farmaceutycznych<\/a> w Nowym Jorku, skontaktuj si\u0119 z Napoli Shkolnik PLLC. Istnieje mo\u017cliwo\u015b\u0107 um\u00f3wienia si\u0119 po godzinach.<\/p>","protected":false},"excerpt":{"rendered":"<p>DES Daughters And Serious Injury Doctors once considered Diethylstilbestrol to be something of a miracle drug which could all but end most pregnancy complications, but instead of a panacea, the&#8230;<\/p>","protected":false},"featured_media":0,"menu_order":61,"template":"","practiceareas_category":[743],"class_list":["post-5909","practiceareas","type-practiceareas","status-publish","hentry","practiceareas_category-pharmaceutical-litigation"],"acf":[],"_links":{"self":[{"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/practiceareas\/5909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/practiceareas"}],"about":[{"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/types\/practiceareas"}],"version-history":[{"count":0,"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/practiceareas\/5909\/revisions"}],"wp:attachment":[{"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/media?parent=5909"}],"wp:term":[{"taxonomy":"practiceareas_category","embeddable":true,"href":"https:\/\/napolilaw.lemonadestand.org\/pl\/wp-json\/wp\/v2\/practiceareas_category?post=5909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}