{"id":5909,"date":"2017-08-01T18:12:29","date_gmt":"2017-08-01T22:12:29","guid":{"rendered":"http:\/\/localhost:10028\/practiceareas\/diethylstilbestrol-des\/"},"modified":"2022-06-21T16:54:49","modified_gmt":"2022-06-21T20:54:49","slug":"dietilestilbestrol-des","status":"publish","type":"practiceareas","link":"https:\/\/napolilaw.lemonadestand.org\/es\/areas-de-practica-2\/dietilestilbestrol-des\/","title":{"rendered":"DES Daughters"},"content":{"rendered":"<h2>Hijas de DES y lesiones graves<\/h2>\n<p>Doctors once considered Diethylstilbestrol to be something of a miracle drug which could all but end most pregnancy complications, but instead of a panacea, the drug created an entire generation of victims.<\/p>\n<p>The synthetic estrogen was created in 1938, and after a brief series of clinical trials, the Food and Drug Administration allowed doctors to prescribe it to pregnant women in 1947. At the time, many doctors believed that low estrogen levels caused most pregnancy complications, and even though that idea was somewhat debunked by the 1950s (and is entirely debunked today), doctors kept administering it in large quantities.<\/p>\n<p>About that same time, researchers began to question DES\u2019 safety, leading to a 1971 FDA declaration that the drug was <a href=\"https:\/\/www.cdc.gov\/des\/consumers\/about\/history.html\" target=\"_blank\" rel=\"noopener noreferrer\">no apto para mujeres embarazadas<\/a>. Pero las recetas continuaron durante varios a\u00f1os m\u00e1s, porque la agencia no retir\u00f3 el medicamento.<\/p>\n<p>&nbsp;<\/p>\n<h3>DES Hijas (e DES Hijos)<\/h3>\n<p>In the 1940s and 1950s, many pregnant women went to general practitioners. These doctors probably had no idea that they were prescribing a powerful drug which was, at best, only marginally effective.<\/p>\n<p>The FDA took adverse action against DES based on a 1971 study which linked Diethylstilbestrol with vaginal clear cell adenocarcinoma, an unusual and aggressive form of <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJM197104222841604\" target=\"_blank\" rel=\"noopener noreferrer\">c\u00e1ncer de cuello uterino<\/a> que es dif\u00edcil de tratar y tiene una alta tasa de mortalidad. Las hijas de DES, o mujeres que estuvieron expuestas a la droga en el \u00fatero, desarrollaron esta enfermedad a un ritmo alarmantemente alto. A lo largo de los a\u00f1os, el dietilestilbestrol tambi\u00e9n se ha relacionado con otros problemas de salud graves, que incluyen:<\/p>\n<ul>\n<li><strong>Infertilidad y Salud Reproductiva<\/strong>: Los cient\u00edficos han clasificado DES como un terat\u00f3geno, un grupo de sustancias que esencialmente envenenan el \u00fatero. M\u00e1s adelante en sus vidas, las mujeres que estuvieron expuestas a la droga mientras estaban en el \u00fatero a menudo se enfrentan a una variedad de problemas reproductivos, incluidos el embarazo ect\u00f3pico, el parto prematuro y el aborto espont\u00e1neo.<\/li>\n<li><strong>C\u00e1ncer de mama<\/strong>: La exposici\u00f3n al DES aumenta el riesgo de c\u00e1ncer de mama, aunque no tanto como el adenocarcinoma vaginal de c\u00e9lulas claras.<\/li>\n<li><strong>Obesidad<\/strong>: DES tambi\u00e9n es un obes\u00f3geno conocido, por lo que las v\u00edctimas a menudo desarrollan obesidad inexplicable en su edad adulta.<\/li>\n<\/ul>\n<p>Los hijos de DES tienen problemas similares, ya que tienen mayores casos de c\u00e1ncer testicular, infertilidad y niveles bajos de testosterona.<\/p>\n<p>&nbsp;<\/p>\n<h3>DES Nietas<\/h3>\n<p>Researchers now know that DES is an epigenetic drug that actually has the power to alter a person\u2019s genetic code. As a result, the physical abnormalities that affect DES daughters and sons may affect their children as well. Many researchers fear that these effects may continue indefinitely as they are passed down from parents to children.<\/p>\n<p>The good news is that the side effects seem to have diminished somewhat, as DES granddaughters and grandsons are likely to have fertility issues but, so far, are not more prone to reproductive cancer. The bad news is that the psychological effects of DES exposure, such as <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20332145\" target=\"_blank\" rel=\"noopener noreferrer\">depresi\u00f3n severa<\/a>, puede ser incluso peor.<\/p>\n<p>&nbsp;<\/p>\n<h3>Reclamaciones por Da\u00f1os<\/h3>\n<p>Because the DES exposure occurred so many years ago, one would think that these cases would be difficult to prove. But two plaintiff-friendly legal rules make the process much easier.<\/p>\n<p>One is the <a href=\"http:\/\/scholarship.law.missouri.edu\/cgi\/viewcontent.cgi?article=1187&amp;context=facpubs\" target=\"_blank\" rel=\"noopener noreferrer\">responsabilidad de cuota de mercado<\/a> doctrine. This rule is now widely used in products liability cases but was actually conceived in a DES daughters case. In most of these cases, the victim\/plaintiff names several potential defendants but, through no fault of his or her own, the victim\/plaintiff cannot identify the actual tortfeasor (company which sold DES to the victim\/plaintiff\u2019s mother). If a substantial share of the possibly responsible companies are named in the lawsuit and the jury awards damages, each defendant is responsible for a share of damages based on its market share at the time the drug was sold.<\/p>\n<p>Another key doctrine is the <a href=\"http:\/\/digitalcommons.law.scu.edu\/cgi\/viewcontent.cgi?article=1930&amp;context=lawreview\" target=\"_blank\" rel=\"noopener noreferrer\">regla de descubrimiento<\/a>. This principle states that the three-year statute of limitations is tolled (suspended) until the victim knows about the injury and has a plausible reason to connect that injury with someone else\u2019s negligence.<\/p>\n<p>Successful plaintiffs are normally entitled to compensatory damages for medical bills, lost wages, emotional distress, loss of enjoyment in life, and other consequential damages, as well as significant punitive damages which punish the tortfeasor\u2019s wrongful conduct and help deter others from doing the same thing.<\/p>\n<p>DES daughters must often deal with lifelong and\/or serious injuries. For a free consultation with a <a href=\"\/es\/litigio-farmaceutico\/\">abogado litigante farmac\u00e9utico<\/a> en Nueva York, p\u00f3ngase en contacto con Napoli Shkolnik PLLC. Hay citas disponibles despu\u00e9s del horario de atenci\u00f3n.<\/p>","protected":false},"excerpt":{"rendered":"<p>DES Daughters And Serious Injury Doctors once considered Diethylstilbestrol to be something of a miracle drug which could all but end most pregnancy complications, but instead of a panacea, the&#8230;<\/p>","protected":false},"featured_media":0,"menu_order":61,"template":"","practiceareas_category":[743],"class_list":["post-5909","practiceareas","type-practiceareas","status-publish","hentry","practiceareas_category-pharmaceutical-litigation"],"acf":[],"_links":{"self":[{"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/practiceareas\/5909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/practiceareas"}],"about":[{"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/types\/practiceareas"}],"version-history":[{"count":0,"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/practiceareas\/5909\/revisions"}],"wp:attachment":[{"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/media?parent=5909"}],"wp:term":[{"taxonomy":"practiceareas_category","embeddable":true,"href":"https:\/\/napolilaw.lemonadestand.org\/es\/wp-json\/wp\/v2\/practiceareas_category?post=5909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}